Endocrine Abstracts

DM 2 is a genetic disorder characterized by reduced insulin action and impaired insulin secretion. Metabolism of healthy Lithuanian citizens with an inherited risk for DM 2 was compared with a control group without a family history of DM 2. 84 normotensive first degree relatives (FDR) (23M, 61F) with at least one parent or sibling with DM 2 were investigated. 89 normotensive and glucose tolerant ubjects without family history of DM 2 and with a comparable distribution of age, ...

Dexamethasone is frequently used in diagnostic work-up of patients suspected of having Cushing's syndrome. We report the case of a young woman whose cortisol production paradoxically increased following dexamethasone administration. A 27 years old woman presented with intermittent facial rounding (see photos), weight gain (6 kg), hirsuitism, spontaneous bruising, menstrual irregularity. On examination the only feature to suggest Cushing's syndrome was very thin skin on the bac...